STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)    
Predicted Functional Partners:
GNAI1
G protein subunit alpha i1.
    
 0.942
GNAI2
G protein subunit alpha i2.
    
 0.942
GNAI3
G protein subunit alpha i3.
    
 0.933
S1PR4
Sphingosine-1-phosphate receptor 4; Belongs to the G-protein coupled receptor 1 family.
     
 
0.900
CD4
Uncharacterized protein.
    
 
 0.560
SPHK1
Sphingosine kinase 1.
      
 0.420
GNA12
G protein subunit alpha 12.
    
 0.411
CD69
CD69 molecule.
    
 0.405
GNAO1
G protein subunit alpha o1.
    
 0.403
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
Server load: high (88%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.