STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM14Uncharacterized protein. (520 aa)    
Predicted Functional Partners:
CBFA2T2
TAFH domain-containing protein.
   
 0.805
NANOG
Homeobox domain-containing protein.
    
 0.713
POU5F1
POU domain protein.
   
 0.632
NANOS3
Nanos-type domain-containing protein; Belongs to the nanos family.
    
 
 0.584
LEF1
Lymphoid enhancer binding factor 1.
    
 0.570
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.561
ESR1
Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
    
 0.558
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.551
E2F4
E2F transcription factor 4.
    
 
 0.550
DAZL
RRM domain-containing protein.
    
 
 0.545
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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