STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CREMcAMP responsive element modulator. (425 aa)    
Predicted Functional Partners:
CREB1
cAMP responsive element binding protein 1.
  
0.949
ATF4
Activating transcription factor 4.
    
 0.929
ATF2
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
     
 0.915
ATF6B
Activating transcription factor 6 beta.
     
 0.907
CREB3L4
cAMP responsive element binding protein 3 like 4.
    
0.906
CREB3L2
BZIP domain-containing protein.
    
 0.905
CREB3
BZIP domain-containing protein.
    
 0.903
BCL2
BCL2 apoptosis regulator.
     
 0.902
CREB3L3
cAMP responsive element binding protein 3 like 3.
    
 0.901
CREB3L1
cAMP responsive element binding protein 3 like 1.
    
0.901
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.