node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABV50369.1 | hemL | P9215_07541 | P9215_05651 | COG1836 Predicted membrane protein [Function unknown]. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.644 |
cobJ | hemA | P9215_17931 | P9215_08621 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.555 |
cobJ | hemB | P9215_17931 | P9215_02351 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.559 |
cobJ | hemC | P9215_17931 | P9215_05771 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.579 |
cobJ | hemD | P9215_17931 | P9215_01311 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.575 |
cobJ | hemE | P9215_17931 | P9215_06651 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.424 |
cobJ | hemL | P9215_17931 | P9215_05651 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.545 |
cobJ | ribD | P9215_17931 | P9215_14901 | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.478 |
guaA | hemB | P9215_00351 | P9215_02351 | GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP. | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.405 |
guaA | hemE | P9215_00351 | P9215_06651 | GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP. | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.464 |
guaA | hemL | P9215_00351 | P9215_05651 | GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP. | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.562 |
guaA | ribD | P9215_00351 | P9215_14901 | GMP synthase, PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.612 |
hemA | cobJ | P9215_08621 | P9215_17931 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | 0.555 |
hemA | hemB | P9215_08621 | P9215_02351 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | 0.871 |
hemA | hemC | P9215_08621 | P9215_05771 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.986 |
hemA | hemD | P9215_08621 | P9215_01311 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.859 |
hemA | hemE | P9215_08621 | P9215_06651 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.634 |
hemA | hemL | P9215_08621 | P9215_05651 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.989 |
hemA | ribD | P9215_08621 | P9215_14901 | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.422 |
hemB | cobJ | P9215_02351 | P9215_17931 | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. | Bifunctional cbiH protein and precorrin-3B C17-methyltransferase; COG1010 Precorrin-3B methylase [Coenzyme metabolism]. | 0.559 |