STRINGSTRING
fabG protein (Staphylococcus aureus COL) - STRING interaction network
"fabG" - 3-oxoacyl-ACP reductase in Staphylococcus aureus COL
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabG3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta- ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (244 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-ACP transacylase (308 aa)
 
 
  0.994
fabZ
(3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (146 aa)
 
  0.966
fabF
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (414 aa)
 
  0.963
fabH
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and/or straight-chain of fatty acids (313 aa)
 
 
  0.945
plsX
Glycerol-3-phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (328 aa)
   
   
  0.932
fapR
Transcription factor fapR; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (190 aa)
              0.907
SACOL0212
3-hydroxyacyl-CoA dehydrogenase (753 aa)
   
 
  0.863
vraB
acetyl-CoA acetyltransferase (379 aa)
   
 
  0.832
SACOL0426
acetyl-CoA acetyltransferase (393 aa)
   
 
  0.832
SACOL0211
acetyl-CoA acetyltransferase (394 aa)
   
 
  0.832
Your Current Organism:
Staphylococcus aureus COL
NCBI taxonomy Id: 93062
Other names: S. aureus subsp. aureus COL, Staphylococcus aureus COL, Staphylococcus aureus subsp. aureus COL
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