STRINGSTRING
hld protein (Staphylococcus aureus COL) - STRING interaction network
"hld" - Delta-hemolysin in Staphylococcus aureus COL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hldDelta-hemolysin; Lyses erythrocytes and many other mammalian cells (44 aa)    
Predicted Functional Partners:
agrB
Accessory gene regulator protein B; Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (189 aa)
         
  0.565
agrD
Accessory gene regulator protein D (46 aa)
         
  0.557
argC2
Accessory gene regulator protein C (430 aa)
         
  0.522
agrA
Accessory gene regulator protein A; Required for high-level post-exponential phase expression of a series of secreted proteins (238 aa)
         
  0.442
Your Current Organism:
Staphylococcus aureus COL
NCBI taxonomy Id: 93062
Other names: S. aureus subsp. aureus COL, Staphylococcus aureus COL, Staphylococcus aureus subsp. aureus COL
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