node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SiRe_0099 | SiRe_0100 | SiRe_0099 | SiRe_0100 | Short-chain dehydrogenase/reductase SDR. | Exodeoxyribonuclease III Xth. | 0.805 |
SiRe_0100 | SiRe_0099 | SiRe_0100 | SiRe_0099 | Exodeoxyribonuclease III Xth. | Short-chain dehydrogenase/reductase SDR. | 0.805 |
SiRe_0100 | SiRe_1280 | SiRe_0100 | SiRe_1280 | Exodeoxyribonuclease III Xth. | Nucleotide excision repair nuclease, Xpf. | 0.738 |
SiRe_0100 | SiRe_1884 | SiRe_0100 | SiRe_1884 | Exodeoxyribonuclease III Xth. | DNA-(apurinic or apyrimidinic site) lyase. | 0.970 |
SiRe_0100 | SiRe_2666 | SiRe_0100 | SiRe_2666 | Exodeoxyribonuclease III Xth. | Xylose isomerase domain protein TIM barrel. | 0.892 |
SiRe_0100 | fen | SiRe_0100 | SiRe_1830 | Exodeoxyribonuclease III Xth. | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] | 0.970 |
SiRe_0100 | lig | SiRe_0100 | SiRe_1818 | Exodeoxyribonuclease III Xth. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.955 |
SiRe_0100 | pcn | SiRe_0100 | SiRe_1048 | Exodeoxyribonuclease III Xth. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.804 |
SiRe_0100 | pcn-2 | SiRe_0100 | SiRe_1594 | Exodeoxyribonuclease III Xth. | DNA polymerase sliding clamp, PRK01115; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.804 |
SiRe_0100 | pcn-3 | SiRe_0100 | SiRe_1602 | Exodeoxyribonuclease III Xth. | DNA polymerase sliding clamp subunit (PCNA like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.804 |
SiRe_0100 | rfcL | SiRe_0100 | SiRe_1234 | Exodeoxyribonuclease III Xth. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.696 |
SiRe_1280 | SiRe_0100 | SiRe_1280 | SiRe_0100 | Nucleotide excision repair nuclease, Xpf. | Exodeoxyribonuclease III Xth. | 0.738 |
SiRe_1280 | SiRe_1884 | SiRe_1280 | SiRe_1884 | Nucleotide excision repair nuclease, Xpf. | DNA-(apurinic or apyrimidinic site) lyase. | 0.411 |
SiRe_1280 | SiRe_2666 | SiRe_1280 | SiRe_2666 | Nucleotide excision repair nuclease, Xpf. | Xylose isomerase domain protein TIM barrel. | 0.678 |
SiRe_1280 | fen | SiRe_1280 | SiRe_1830 | Nucleotide excision repair nuclease, Xpf. | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] | 0.967 |
SiRe_1280 | pcn | SiRe_1280 | SiRe_1048 | Nucleotide excision repair nuclease, Xpf. | Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.754 |
SiRe_1280 | pcn-2 | SiRe_1280 | SiRe_1594 | Nucleotide excision repair nuclease, Xpf. | DNA polymerase sliding clamp, PRK01115; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.733 |
SiRe_1280 | pcn-3 | SiRe_1280 | SiRe_1602 | Nucleotide excision repair nuclease, Xpf. | DNA polymerase sliding clamp subunit (PCNA like protein); Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.722 |
SiRe_1280 | rfcL | SiRe_1280 | SiRe_1234 | Nucleotide excision repair nuclease, Xpf. | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.727 |
SiRe_1884 | SiRe_0100 | SiRe_1884 | SiRe_0100 | DNA-(apurinic or apyrimidinic site) lyase. | Exodeoxyribonuclease III Xth. | 0.970 |