STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carCcaffeyl-CoA reductase CarC; The Caffeyl-CoA reductase-Etf complex catalyzes the reduction of caffeyl-CoA to yield hydrocaffeyl-CoA. It couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. Also reduces 4-coumaroyl-CoA and feruloyl-CoA. (379 aa)    
Predicted Functional Partners:
carD
Electron transfer flavoprotein beta subunit CarD; Caffeyl-CoA reductase-Etf complex catalyzes the reduction of caffeyl-CoA to yield hydrocaffeyl-CoA. It couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. The electron transfer flavoprotein (Etf) mediates the electron transfer between the different donors and acceptors. The complex can also reduce 4-coumaroyl-CoA and feruloyl-CoA.
 
 
 0.999
carE
Electron transfer flavoprotein alpha subunit CarE; Caffeyl-CoA reductase-Etf complex catalyzes the reduction of caffeyl-CoA to yield hydrocaffeyl-CoA. It couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant. It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction. The electron transfer flavoprotein (Etf) mediates the electron transfer between the different donors and acceptors. The iron- sulfur cluster may be involved in electron transport, possibly in the [...]
 0.999
etfA
Electron transfer flavoprotein alpha subunit EtfA.
 
 0.994
etfB
Electron transfer flavoprotein beta-subunit EtfB.
 
 
 0.982
AFA49074.1
acyl-CoA synthetase.
 
 
 0.949
carB2
caffeyl-CoA-synthetase CarB2.
 
  
 0.937
carA2
CoA transferase CarA2; Belongs to the 3-oxoacid CoA-transferase family.
 
  
 0.893
carB1
Carbamoyl-phosphate synthase large subunit CarB1.
      
 0.789
hydB
Iron hydrogenase HydB.
  
 
 0.782
nifJ
Pyruvate:ferredoxin oxidoreductase NifJ; Flavodoxin.
  
 
 0.754
Your Current Organism:
Acetobacterium woodii
NCBI taxonomy Id: 931626
Other names: A. woodii DSM 1030, Acetobacterium woodii ATCC 29683, Acetobacterium woodii DSM 1030, Acetobacterium woodii WB1
Server load: low (24%) [HD]