STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT25_014114Uncharacterized protein. (576 aa)    
Predicted Functional Partners:
CVT25_008313
Uncharacterized protein.
    
 0.997
CVT25_013851
SGF29 C-terminal domain-containing protein.
    
 0.996
CVT25_009843
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.992
CVT25_012655
Uncharacterized protein.
    
 0.988
CVT25_000564
Ubiquitin carboxyl-terminal hydrolase.
    
 0.986
CVT25_010890
Uncharacterized protein.
   
 0.982
CVT25_003380
TFIID_20kDa domain-containing protein.
    
 0.979
CVT25_000261
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.978
CVT25_006309
Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
   
 0.978
SUS1
Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]
    
 0.976
Your Current Organism:
Psilocybe cyanescens
NCBI taxonomy Id: 93625
Other names: P. cyanescens, PRM 901481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.