STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGNGPI ethanolamine phosphate transferase 1. (890 aa)    
Predicted Functional Partners:
PIGB
Mannosyltransferase.
     
 0.967
PIGV
Phosphatidylinositol glycan anchor biosynthesis class V.
   
 0.943
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.866
PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A.
     
 0.813
PIGL
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase isoform X1.
      
 0.768
PIGG
GPI ethanolamine phosphate transferase 2 isoform X1.
      
0.766
PIGF
Phosphatidylinositol-glycan biosynthesis class F protein isoform X2.
    
 0.752
COASY
Bifunctional coenzyme A synthase isoform X3.
    
  0.744
NRL
Neural retina-specific leucine zipper protein.
      
 0.721
FGD2
FYVE, RhoGEF and PH domain-containing protein 2.
   
    0.705
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.