STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.999
PTCH1
Protein patched homolog 1.
   
 0.984
SPOP
Speckle-type POZ protein.
   
 0.972
KIF7
LOW QUALITY PROTEIN: kinesin-like protein KIF7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.965
SPOPL
Speckle-type POZ protein-like isoform X1.
   
 0.954
ENSEEUP00000005639
annotation not available
   
0.953
BTRC
F-box/WD repeat-containing protein 1A isoform X1.
    
 0.946
ENSEEUP00000003494
annotation not available
    
 0.939
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.930
KIF3A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
 0.921
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.