STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (774 aa)    
Predicted Functional Partners:
NRP1
Keratinocyte proline-rich protein-like.
    
 0.981
PLXNC1
plexin-C1.
    
 0.871
ENSEEUP00000004933
annotation not available
    
 0.858
PLXNA4
plexin-A4 isoform X1.
    
 0.854
MST1R
Macrophage-stimulating protein receptor.
    
 0.792
MET
Hepatocyte growth factor receptor.
    
 0.792
ENSEEUP00000001176
annotation not available
    
 0.701
ENSEEUP00000007687
annotation not available
    
 0.701
NRP2
Neuropilin; Belongs to the neuropilin family.
    
 
 0.694
LOC103128324
plexin-B2-like.
    
 0.663
Your Current Organism:
Erinaceus europaeus
NCBI taxonomy Id: 9365
Other names: E. europaeus, European hedgehog, common hedgehog, western European hedgehog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.