STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK2Cell division protein kinase 2; Belongs to the protein kinase superfamily. (346 aa)    
Predicted Functional Partners:
CCNE1
G1/S-specific cyclin-E1; Belongs to the cyclin family.
   
 0.999
L5KA29_PTEAL
Cyclin-A2; Belongs to the cyclin family.
   
 0.999
CCNA1
Cyclin-A1; Belongs to the cyclin family.
   
 0.999
CDC6
Cell division control protein 6 like protein.
   
 0.998
SKP2
S-phase kinase-associated protein 2.
   
 0.998
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.998
SKP1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.995
RB1
Retinoblastoma-associated protein.
   
 0.995
CCND1
G1/S-specific cyclin-D1; Belongs to the cyclin family.
   
 0.993
E2F1
Transcription factor E2F1.
   
 0.988
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.