STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (296 aa)    
Predicted Functional Partners:
L5KMH8_PTEAL
Cell division protein kinase 6; Belongs to the protein kinase superfamily.
   
 0.999
CDK4
Cell division protein kinase 4; Belongs to the protein kinase superfamily.
   
 0.999
CDKN1A
Cyclin-dependent kinase inhibitor 1.
   
 0.997
CDK2
Cell division protein kinase 2; Belongs to the protein kinase superfamily.
   
 0.993
RB1
Retinoblastoma-associated protein.
    
 0.990
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
   
 0.984
CCNE1
G1/S-specific cyclin-E1; Belongs to the cyclin family.
   
0.967
RBL1
Retinoblastoma-like protein 1.
    
 0.966
CDKN2C
Cyclin-dependent kinase 4 inhibitor C.
    
 0.960
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.957
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.