STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)    
Predicted Functional Partners:
PAFAH1B2
Platelet-activating factor acetylhydrolase IB subunit beta.
    
 0.998
PAFAH1B3
Platelet-activating factor acetylhydrolase IB subunit gamma.
    
 0.996
L5JPD2_PTEAL
Cytoplasmic dynein 1 heavy chain 1.
   
 0.959
NUDC
Nuclear migration protein nudC.
   
 0.950
PAFAH2
Platelet-activating factor acetylhydrolase.
     
 0.939
DCTN2
Dynactin subunit 2.
    
 0.935
DCTN1
Dynactin subunit 1.
    
 0.934
NDEL1
Nuclear distribution protein nudE-like 1.
    
 
 0.924
DYNLL1
Dynein light chain.
    
 0.908
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
     
  0.900
Your Current Organism:
Pteropus alecto
NCBI taxonomy Id: 9402
Other names: P. alecto, black flying fox
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.