node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK46940.1 | fis | Shewana3_0702 | Shewana3_0398 | Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS). | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.597 |
ABK46940.1 | rnpA | Shewana3_0702 | Shewana3_0008 | Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS). | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.446 |
ABK46940.1 | rpsR | Shewana3_0702 | Shewana3_0703 | Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS). | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.987 |
ABK46940.1 | rpsT | Shewana3_0702 | Shewana3_3140 | Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS). | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.474 |
dusA | fis | Shewana3_0718 | Shewana3_0398 | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.669 |
dusB | fis | Shewana3_0399 | Shewana3_0398 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.962 |
dusB | polA | Shewana3_0399 | Shewana3_4109 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.407 |
dusB | prmA | Shewana3_0399 | Shewana3_0400 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | LSU ribosomal protein L11P methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.569 |
dusB | rnpA | Shewana3_0399 | Shewana3_0008 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.638 |
dusB | rpsR | Shewana3_0399 | Shewana3_0703 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.477 |
dusB | rpsT | Shewana3_0399 | Shewana3_3140 | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.481 |
dusC | fis | Shewana3_2452 | Shewana3_0398 | Dihydrouridine synthase, DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.669 |
fis | ABK46940.1 | Shewana3_0398 | Shewana3_0702 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Single-strand binding protein/Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS). | 0.597 |
fis | dusA | Shewana3_0398 | Shewana3_0718 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.669 |
fis | dusB | Shewana3_0398 | Shewana3_0399 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.962 |
fis | dusC | Shewana3_0398 | Shewana3_2452 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Dihydrouridine synthase, DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.669 |
fis | polA | Shewana3_0398 | Shewana3_4109 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.701 |
fis | prmA | Shewana3_0398 | Shewana3_0400 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | LSU ribosomal protein L11P methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | 0.569 |
fis | rnpA | Shewana3_0398 | Shewana3_0008 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.473 |
fis | rpoZ | Shewana3_0398 | Shewana3_3811 | Helix-turn-helix, Fis-type; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.598 |