node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK47225.1 | ABK47226.1 | Shewana3_0990 | Shewana3_0991 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.593 |
ABK47225.1 | ABK47787.1 | Shewana3_0990 | Shewana3_1553 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | 0.594 |
ABK47225.1 | ABK49256.1 | Shewana3_0990 | Shewana3_3031 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.533 |
ABK47225.1 | ABK49837.1 | Shewana3_0990 | Shewana3_3615 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.588 |
ABK47225.1 | bamC | Shewana3_0990 | Shewana3_1657 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.504 |
ABK47225.1 | dsbB | Shewana3_0990 | Shewana3_1633 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.488 |
ABK47225.1 | lipA | Shewana3_0990 | Shewana3_0988 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.850 |
ABK47225.1 | lipB | Shewana3_0990 | Shewana3_0989 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.886 |
ABK47225.1 | lptE | Shewana3_0990 | Shewana3_1000 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.589 |
ABK47225.1 | rraB | Shewana3_0990 | Shewana3_0569 | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.590 |
ABK47226.1 | ABK47225.1 | Shewana3_0991 | Shewana3_0990 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | 0.593 |
ABK47226.1 | lipA | Shewana3_0991 | Shewana3_0988 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.441 |
ABK47226.1 | lipB | Shewana3_0991 | Shewana3_0989 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.441 |
ABK47787.1 | ABK47225.1 | Shewana3_1553 | Shewana3_0990 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | 0.594 |
ABK47787.1 | ABK49256.1 | Shewana3_1553 | Shewana3_3031 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish [...] | 0.765 |
ABK47787.1 | ABK49837.1 | Shewana3_1553 | Shewana3_3615 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis. | 0.760 |
ABK47787.1 | bamC | Shewana3_1553 | Shewana3_1657 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.705 |
ABK47787.1 | dsbB | Shewana3_1553 | Shewana3_1633 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.694 |
ABK47787.1 | lptE | Shewana3_1553 | Shewana3_1000 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.679 |
ABK47787.1 | rraB | Shewana3_1553 | Shewana3_0569 | PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein. | Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.773 |