node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK47331.1 | birA | Shewana3_1096 | Shewana3_0183 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.747 |
ABK47331.1 | rlmL | Shewana3_1096 | Shewana3_1601 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.736 |
ABK47331.1 | uppS | Shewana3_1096 | Shewana3_2811 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.531 |
ABK47836.1 | ABK47837.1 | Shewana3_1602 | Shewana3_1603 | PFAM: glutaredoxin; glutaredoxin 2; KEGG: son:SO1852 hypothetical protein. | PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1853 ABC transporter, ATP-binding protein. | 0.801 |
ABK47836.1 | ABK47838.1 | Shewana3_1602 | Shewana3_1604 | PFAM: glutaredoxin; glutaredoxin 2; KEGG: son:SO1852 hypothetical protein. | KEGG: son:SO1854 hypothetical protein. | 0.719 |
ABK47836.1 | rlmL | Shewana3_1602 | Shewana3_1601 | PFAM: glutaredoxin; glutaredoxin 2; KEGG: son:SO1852 hypothetical protein. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.812 |
ABK47837.1 | ABK47836.1 | Shewana3_1603 | Shewana3_1602 | PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1853 ABC transporter, ATP-binding protein. | PFAM: glutaredoxin; glutaredoxin 2; KEGG: son:SO1852 hypothetical protein. | 0.801 |
ABK47837.1 | ABK47838.1 | Shewana3_1603 | Shewana3_1604 | PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1853 ABC transporter, ATP-binding protein. | KEGG: son:SO1854 hypothetical protein. | 0.719 |
ABK47837.1 | rlmL | Shewana3_1603 | Shewana3_1601 | PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1853 ABC transporter, ATP-binding protein. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.854 |
ABK47838.1 | ABK47836.1 | Shewana3_1604 | Shewana3_1602 | KEGG: son:SO1854 hypothetical protein. | PFAM: glutaredoxin; glutaredoxin 2; KEGG: son:SO1852 hypothetical protein. | 0.719 |
ABK47838.1 | ABK47837.1 | Shewana3_1604 | Shewana3_1603 | KEGG: son:SO1854 hypothetical protein. | PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1853 ABC transporter, ATP-binding protein. | 0.719 |
ABK47838.1 | rlmL | Shewana3_1604 | Shewana3_1601 | KEGG: son:SO1854 hypothetical protein. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.747 |
argS | pnp | Shewana3_3673 | Shewana3_1035 | TIGRFAM: arginyl-tRNA synthetase; KEGG: son:SO4123 arginyl-tRNA synthetase. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.595 |
argS | rlmL | Shewana3_3673 | Shewana3_1601 | TIGRFAM: arginyl-tRNA synthetase; KEGG: son:SO4123 arginyl-tRNA synthetase. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.543 |
argS | thiI | Shewana3_3673 | Shewana3_2896 | TIGRFAM: arginyl-tRNA synthetase; KEGG: son:SO4123 arginyl-tRNA synthetase. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.440 |
birA | ABK47331.1 | Shewana3_0183 | Shewana3_1096 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.747 |
birA | rlmL | Shewana3_0183 | Shewana3_1601 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.549 |
pnp | argS | Shewana3_1035 | Shewana3_3673 | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | TIGRFAM: arginyl-tRNA synthetase; KEGG: son:SO4123 arginyl-tRNA synthetase. | 0.595 |
pnp | rlmL | Shewana3_1035 | Shewana3_1601 | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.608 |
pnp | uppS | Shewana3_1035 | Shewana3_2811 | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.718 |