node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK47057.1 | gcvP | Shewana3_0819 | Shewana3_3499 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.808 |
ABK47057.1 | pdxH | Shewana3_0819 | Shewana3_1626 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.480 |
ABK47057.1 | pdxJ | Shewana3_0819 | Shewana3_3023 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.503 |
ABK47057.1 | ribB-2 | Shewana3_0819 | Shewana3_1098 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.552 |
ABK47331.1 | pdxH | Shewana3_1096 | Shewana3_1626 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.430 |
ABK47331.1 | pdxJ | Shewana3_1096 | Shewana3_3023 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.579 |
ABK47331.1 | ribB-2 | Shewana3_1096 | Shewana3_1098 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
ABK47858.1 | ABK47860.1 | Shewana3_1625 | Shewana3_1627 | PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative. | PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein; Belongs to the UPF0178 family. | 0.405 |
ABK47858.1 | pdxH | Shewana3_1625 | Shewana3_1626 | PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.431 |
ABK47860.1 | ABK47858.1 | Shewana3_1627 | Shewana3_1625 | PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein; Belongs to the UPF0178 family. | PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative. | 0.405 |
ABK47860.1 | ABK47861.1 | Shewana3_1627 | Shewana3_1628 | PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein; Belongs to the UPF0178 family. | PFAM: YceI family protein; KEGG: son:SO2893 hypothetical protein; Belongs to the UPF0312 family. | 0.476 |
ABK47860.1 | pdxH | Shewana3_1627 | Shewana3_1626 | PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein; Belongs to the UPF0178 family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.723 |
ABK47861.1 | ABK47860.1 | Shewana3_1628 | Shewana3_1627 | PFAM: YceI family protein; KEGG: son:SO2893 hypothetical protein; Belongs to the UPF0312 family. | PFAM: protein of unknown function DUF188; KEGG: son:SO2894 YaiI/YqxD family protein; Belongs to the UPF0178 family. | 0.476 |
ABK47861.1 | pdxH | Shewana3_1628 | Shewana3_1626 | PFAM: YceI family protein; KEGG: son:SO2893 hypothetical protein; Belongs to the UPF0312 family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.445 |
gcvP | ABK47057.1 | Shewana3_3499 | Shewana3_0819 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.808 |
gcvP | pdxH | Shewana3_3499 | Shewana3_1626 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.538 |
nnrD | pdxH | Shewana3_0592 | Shewana3_1626 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.430 |
pdxA | pdxH | Shewana3_3208 | Shewana3_1626 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.434 |
pdxA | pdxJ | Shewana3_3208 | Shewana3_3023 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.927 |
pdxA | ribB-2 | Shewana3_3208 | Shewana3_1098 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.495 |