node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK47374.1 | ABK49232.1 | Shewana3_1139 | Shewana3_3007 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.867 |
ABK47374.1 | ABK49237.1 | Shewana3_1139 | Shewana3_3012 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: son:SO1362 prephenate dehydrogenase/chorismate mutase. | 0.817 |
ABK47374.1 | ABK49835.1 | Shewana3_1139 | Shewana3_3613 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.994 |
ABK47374.1 | aroA | Shewana3_1139 | Shewana3_1975 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.712 |
ABK47374.1 | aroB | Shewana3_1139 | Shewana3_3893 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.548 |
ABK47374.1 | aroC | Shewana3_1139 | Shewana3_1469 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.615 |
ABK47374.1 | aroE | Shewana3_1139 | Shewana3_0043 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.632 |
ABK47374.1 | aroK | Shewana3_1139 | Shewana3_3894 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.477 |
ABK47374.1 | serC | Shewana3_1139 | Shewana3_1973 | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.633 |
ABK49232.1 | ABK47374.1 | Shewana3_3007 | Shewana3_1139 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.867 |
ABK49232.1 | ABK49237.1 | Shewana3_3007 | Shewana3_3012 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: son:SO1362 prephenate dehydrogenase/chorismate mutase. | 0.998 |
ABK49232.1 | ABK49835.1 | Shewana3_3007 | Shewana3_3613 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.855 |
ABK49232.1 | aroA | Shewana3_3007 | Shewana3_1975 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.990 |
ABK49232.1 | aroB | Shewana3_3007 | Shewana3_3893 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.955 |
ABK49232.1 | aroC | Shewana3_3007 | Shewana3_1469 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
ABK49232.1 | aroE | Shewana3_3007 | Shewana3_0043 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.907 |
ABK49232.1 | aroK | Shewana3_3007 | Shewana3_3894 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.907 |
ABK49232.1 | cmk | Shewana3_3007 | Shewana3_1976 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: son:SO2403 cytidylate kinase. | 0.615 |
ABK49232.1 | serC | Shewana3_3007 | Shewana3_1973 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: son:SO1367 prephenate dehydratase/chorismate mutase/phospho-2-dehydro-3-deoxyheptonate aldolase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.938 |
ABK49237.1 | ABK47374.1 | Shewana3_3012 | Shewana3_1139 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: son:SO1362 prephenate dehydrogenase/chorismate mutase. | TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: son:SO3415 aspartokinase I/homoserine dehydrogenase, threonine-sensitive; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.817 |