node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK46497.1 | htpX | Shewana3_0254 | Shewana3_2512 | PFAM: protein of unknown function, Spy-related; KEGG: son:SO4476 spheroplast protein y precursor, putative. | HtpX peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: son:SO2728 peptidase HtpX; Belongs to the peptidase M48B family. | 0.526 |
ABK48290.1 | htpX | Shewana3_2060 | Shewana3_2512 | PFAM: protein of unknown function UPF0005; KEGG: son:SO2375 membrane protein, putative; Belongs to the BI1 family. | HtpX peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: son:SO2728 peptidase HtpX; Belongs to the peptidase M48B family. | 0.533 |
ABK48290.1 | msrA-2 | Shewana3_2060 | Shewana3_2393 | PFAM: protein of unknown function UPF0005; KEGG: son:SO2375 membrane protein, putative; Belongs to the BI1 family. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.588 |
ABK48671.1 | ABK49796.1 | Shewana3_2442 | Shewana3_3574 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | PFAM: FxsA cytoplasmic membrane protein; KEGG: son:SO0698 FxsA protein. | 0.661 |
ABK48671.1 | clpB | Shewana3_2442 | Shewana3_3169 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.428 |
ABK48671.1 | ftsH | Shewana3_2442 | Shewana3_1023 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.403 |
ABK48671.1 | groS | Shewana3_2442 | Shewana3_3568 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.591 |
ABK48671.1 | grpE | Shewana3_2442 | Shewana3_2902 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.817 |
ABK48671.1 | htpX | Shewana3_2442 | Shewana3_2512 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | HtpX peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: son:SO2728 peptidase HtpX; Belongs to the peptidase M48B family. | 0.506 |
ABK48671.1 | lon | Shewana3_2442 | Shewana3_2659 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | Lon-A peptidase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.537 |
ABK48671.1 | msrA-2 | Shewana3_2442 | Shewana3_2393 | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.465 |
ABK49796.1 | ABK48671.1 | Shewana3_3574 | Shewana3_2442 | PFAM: FxsA cytoplasmic membrane protein; KEGG: son:SO0698 FxsA protein. | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | 0.661 |
ABK49796.1 | htpX | Shewana3_3574 | Shewana3_2512 | PFAM: FxsA cytoplasmic membrane protein; KEGG: son:SO0698 FxsA protein. | HtpX peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: son:SO2728 peptidase HtpX; Belongs to the peptidase M48B family. | 0.455 |
clpB | ABK48671.1 | Shewana3_3169 | Shewana3_2442 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: Thioredoxin domain; KEGG: son:SO2017 putative thioredoxin-like protein. | 0.428 |
clpB | ftsH | Shewana3_3169 | Shewana3_1023 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.470 |
clpB | groS | Shewana3_3169 | Shewana3_3568 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.744 |
clpB | grpE | Shewana3_3169 | Shewana3_2902 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.859 |
clpB | htpX | Shewana3_3169 | Shewana3_2512 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | HtpX peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: son:SO2728 peptidase HtpX; Belongs to the peptidase M48B family. | 0.527 |
clpB | lon | Shewana3_3169 | Shewana3_2659 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Lon-A peptidase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.676 |
clpB | msrA-2 | Shewana3_3169 | Shewana3_2393 | ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.481 |