STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate; Belongs to the pantothenate synthetase family (281 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family
 
 0.999
ABK47018.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
 
  
 0.964
coaA
TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: son:SO0215 pantothenate kinase
     
 0.911
ABK49330.1
PFAM: aminotransferase class-III; KEGG: son:SO3497 aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
     
 0.911
ABK48913.1
PFAM: Pyridoxal-dependent decarboxylase; KEGG: son:SO1769 glutamate decarboxylase, putative
  
 
  0.905
ABK49315.1
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO1276 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
     
  0.900
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: son:SO2403 cytidylate kinase; Belongs to the cytidylate kinase family. Type 1 subfamily
 
    0.887
ABK49989.1
Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family
  
 
 0.863
ABK49630.1
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
 
  
 0.795
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
  
  
 0.746
Your Current Organism:
Shewanella sp. ANA3
NCBI taxonomy Id: 94122
Other names: S. sp. ANA-3, Shewanella sp. ANA-3, Shewanella sp. ANA3, Shewanella sp. arsenana, Shewanella trabarsenatis
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