node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABK46603.1 | ABK46671.1 | Shewana3_0360 | Shewana3_0428 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | 0.903 |
ABK46603.1 | ABK49274.1 | Shewana3_0360 | Shewana3_3050 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | 0.532 |
ABK46603.1 | gcvH | Shewana3_0360 | Shewana3_3500 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.917 |
ABK46603.1 | gcvP | Shewana3_0360 | Shewana3_3499 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.937 |
ABK46603.1 | gcvT | Shewana3_0360 | Shewana3_3501 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.939 |
ABK46603.1 | glyA | Shewana3_0360 | Shewana3_1094 | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.939 |
ABK46671.1 | ABK46603.1 | Shewana3_0428 | Shewana3_0360 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V. | 0.903 |
ABK46671.1 | ABK47057.1 | Shewana3_0428 | Shewana3_0819 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.827 |
ABK46671.1 | ABK47943.1 | Shewana3_0428 | Shewana3_1710 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region; KEGG: son:SO1930 2-oxoglutarate dehydrogenase E1 component. | 0.996 |
ABK46671.1 | ABK49274.1 | Shewana3_0428 | Shewana3_3050 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | 0.905 |
ABK46671.1 | gcvH | Shewana3_0428 | Shewana3_3500 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.980 |
ABK46671.1 | gcvP | Shewana3_0428 | Shewana3_3499 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.955 |
ABK46671.1 | gcvT | Shewana3_0428 | Shewana3_3501 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.961 |
ABK46671.1 | glyA | Shewana3_0428 | Shewana3_1094 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.924 |
ABK46671.1 | lipA | Shewana3_0428 | Shewana3_0988 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.648 |
ABK46671.1 | lipB | Shewana3_0428 | Shewana3_0989 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.529 |
ABK47057.1 | ABK46671.1 | Shewana3_0819 | Shewana3_0428 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: son:SO0426 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase. | 0.827 |
ABK47057.1 | ABK49274.1 | Shewana3_0819 | Shewana3_3050 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: son:SO1325 glutamate synthase (NADPH) large chain. | 0.942 |
ABK47057.1 | gcvH | Shewana3_0819 | Shewana3_3500 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.876 |
ABK47057.1 | gcvP | Shewana3_0819 | Shewana3_3499 | Delta-1-pyrroline-5-carboxylate dehydrogenase / L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.808 |