STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP19A1Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (503 aa)    
Predicted Functional Partners:
HSD3B1
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.974
HSD17B1
17-beta-hydroxysteroid dehydrogenase type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.972
HSD17B3
Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.958
HSD17B2
Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.953
CYP17A1
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
0.953
HSD17B12
Estradiol 17-beta-dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.951
CYP1A1
Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.
  
0.950
H9KWW2_CALJA
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.945
CYP3A21
Cytochrome P450 3A21; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  
0.942
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
     
 0.940
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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