node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF2 | ATF4 | ENSCJAP00000015097 | ENSCJAP00000004703 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | Activating transcription factor 4. | 0.940 |
ATF2 | ATF6B | ENSCJAP00000015097 | ENSCJAP00000052186 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | 0.951 |
ATF2 | CEBPB | ENSCJAP00000015097 | ENSCJAP00000057589 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | CCAAT/enhancer-binding protein. | 0.403 |
ATF2 | CREB5 | ENSCJAP00000015097 | ENSCJAP00000015407 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. | 0.967 |
ATF2 | CREBBP | ENSCJAP00000015097 | ENSCJAP00000036680 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | CREB-binding protein isoform a. | 0.972 |
ATF2 | EP300 | ENSCJAP00000015097 | ENSCJAP00000008779 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | E1A binding protein p300. | 0.936 |
ATF4 | ATF2 | ENSCJAP00000004703 | ENSCJAP00000015097 | Activating transcription factor 4. | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | 0.940 |
ATF4 | ATF6B | ENSCJAP00000004703 | ENSCJAP00000052186 | Activating transcription factor 4. | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | 0.949 |
ATF4 | CEBPB | ENSCJAP00000004703 | ENSCJAP00000057589 | Activating transcription factor 4. | CCAAT/enhancer-binding protein. | 0.946 |
ATF4 | CREB5 | ENSCJAP00000004703 | ENSCJAP00000015407 | Activating transcription factor 4. | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. | 0.948 |
ATF4 | CREBBP | ENSCJAP00000004703 | ENSCJAP00000036680 | Activating transcription factor 4. | CREB-binding protein isoform a. | 0.962 |
ATF4 | DDIT3 | ENSCJAP00000004703 | ENSCJAP00000043609 | Activating transcription factor 4. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.991 |
ATF4 | EIF2AK3 | ENSCJAP00000004703 | ENSCJAP00000050396 | Activating transcription factor 4. | Eukaryotic translation initiation factor 2-alpha kinase 3. | 0.967 |
ATF4 | EIF2S1 | ENSCJAP00000004703 | ENSCJAP00000028344 | Activating transcription factor 4. | Eukaryotic translation initiation factor 2 subunit alpha. | 0.973 |
ATF4 | ENSCJAP00000059748 | ENSCJAP00000004703 | ENSCJAP00000059748 | Activating transcription factor 4. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.991 |
ATF4 | EP300 | ENSCJAP00000004703 | ENSCJAP00000008779 | Activating transcription factor 4. | E1A binding protein p300. | 0.964 |
ATF6B | ATF2 | ENSCJAP00000052186 | ENSCJAP00000015097 | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | 0.951 |
ATF6B | ATF4 | ENSCJAP00000052186 | ENSCJAP00000004703 | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | Activating transcription factor 4. | 0.949 |
ATF6B | CREB5 | ENSCJAP00000052186 | ENSCJAP00000015407 | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. | 0.908 |
ATF6B | DDIT3 | ENSCJAP00000052186 | ENSCJAP00000043609 | Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.935 |