STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PGCGastricsin; Hydrolyzes a variety of proteins. (414 aa)    
Predicted Functional Partners:
KLK5
Kallikrein related peptidase 5; Belongs to the peptidase S1 family.
    
 
 0.561
DPYD
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
      
 0.548
AGT
Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.
   
 0.548
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
    
 
 0.523
PGM1
Uncharacterized protein; Belongs to the phosphohexose mutase family.
   
 
 0.523
DEFB114
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.507
RNF123
E3 ubiquitin-protein ligase RNF123.
      
 0.506
KLK7
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
    
 
 0.505
DISC1
Disrupted in schizophrenia 1 protein isoform L.
    
 
 0.494
CTSS
Cathepsin S isoform 1 preproprotein; Belongs to the peptidase C1 family.
   
 0.441
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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