STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDF1Inactive rhomboid protein 1; Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. (867 aa)    
Predicted Functional Partners:
ADAM17
Disintegrin and metalloproteinase domain-containing protein 17 preproprotein.
    
 0.771
FRMD8
FERM domain containing 8.
     
 0.733
ADAM7
ADAM metallopeptidase domain 7.
      
 0.584
AREG
Amphiregulin.
      
 0.567
MAP6D1
Rhomboid domain-containing protein.
      
 0.516
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10.
    
 0.507
HBEGF
Heparin binding EGF like growth factor.
      
 0.502
CNIH1-2
Uncharacterized protein.
      
 0.465
CNIH1
Uncharacterized protein.
      
 0.465
METTL23
Methyltransferase-like protein 23 isoform 1.
    
 
 0.462
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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