node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGA | FSHR | ENSCJAP00000001086 | ENSCJAP00000047613 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.918 |
CGA | LHCGR | ENSCJAP00000001086 | ENSCJAP00000019804 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | 0.790 |
CGA | LOC100391685 | ENSCJAP00000001086 | ENSCJAP00000000359 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.977 |
CGA | TSHR | ENSCJAP00000001086 | ENSCJAP00000031540 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.923 |
DHX34 | LOC100391685 | ENSCJAP00000021190 | ENSCJAP00000000359 | DExH-box helicase 34. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.894 |
DHX34 | SYT3 | ENSCJAP00000021190 | ENSCJAP00000074119 | DExH-box helicase 34. | Synaptotagmin 3. | 0.916 |
ENSCJAP00000079086 | LOC100391685 | ENSCJAP00000079086 | ENSCJAP00000000359 | Uncharacterized protein. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.585 |
FANCA | LOC100391685 | ENSCJAP00000019737 | ENSCJAP00000000359 | FA complementation group A. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.585 |
FOS | LOC100391685 | ENSCJAP00000073368 | ENSCJAP00000000359 | Proto-oncogene c-Fos. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.644 |
FSHR | CGA | ENSCJAP00000047613 | ENSCJAP00000001086 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.918 |
FSHR | LHCGR | ENSCJAP00000047613 | ENSCJAP00000019804 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | 0.433 |
FSHR | LOC100391685 | ENSCJAP00000047613 | ENSCJAP00000000359 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.650 |
FSHR | TSHR | ENSCJAP00000047613 | ENSCJAP00000031540 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.413 |
LHCGR | CGA | ENSCJAP00000019804 | ENSCJAP00000001086 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.790 |
LHCGR | FSHR | ENSCJAP00000019804 | ENSCJAP00000047613 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.433 |
LHCGR | LOC100391685 | ENSCJAP00000019804 | ENSCJAP00000000359 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | 0.980 |
LHCGR | TSHR | ENSCJAP00000019804 | ENSCJAP00000031540 | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.444 |
LOC100391685 | CGA | ENSCJAP00000000359 | ENSCJAP00000001086 | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.977 |
LOC100391685 | DHX34 | ENSCJAP00000000359 | ENSCJAP00000021190 | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | DExH-box helicase 34. | 0.894 |
LOC100391685 | ENSCJAP00000079086 | ENSCJAP00000000359 | ENSCJAP00000079086 | Choriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy; Belongs to the glycoprotein hormones subunit beta family. | Uncharacterized protein. | 0.585 |