STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSTSomatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. (116 aa)    
Predicted Functional Partners:
SSTR2
Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 0.997
SSTR5
Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family.
   
 0.993
SSTR1
Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 0.991
SSTR3
Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family.
   
 0.984
CENPS-CORT
CENPS-CORT readthrough.
   
 
 0.983
SSTR4
Somatostatin receptor 4; Belongs to the G-protein coupled receptor 1 family.
   
 0.981
NPY
Neuropeptide Y.
   
 
 0.932
PVALB
Parvalbumin; Belongs to the parvalbumin family.
      
 0.916
GAL
Galanin and GMAP prepropeptide.
   
 
 0.882
CCK
Cholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion; Belongs to the gastrin/cholecystokinin family.
   
  
 0.877
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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