STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF3Rho guanine nucleotide exchange factor 3; Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. (558 aa)    
Predicted Functional Partners:
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.777
RHOB
Ras homolog gene family, member B.
    
 0.754
GNA13
G protein subunit alpha 13.
    
 0.723
RHOA
Uncharacterized protein.
    
 0.705
ITSN2
Intersectin 2.
    
0.699
RHOC
Ras homolog family member C.
    
 0.673
RND3
Rho family GTPase 3.
    
 0.650
RND1
Uncharacterized protein.
    
 0.650
RHOF
Ras homolog family member F, filopodia associated.
    
 0.641
CTNS
Cystinosin, lysosomal cystine transporter.
   
  
 0.617
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.