STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)    
Predicted Functional Partners:
LGALS9
Galectin.
    
 0.875
LAG3
Lymphocyte activating 3.
   
  
 0.722
CD80
CD80 molecule.
   
 0.682
TIGIT
T cell immunoreceptor with Ig and ITIM domains.
   
  
 0.679
CEACAM1
Uncharacterized protein.
   
 0.671
PDCD1
Programmed cell death 1.
   
 0.670
LCK
Tyrosine-protein kinase.
   
 0.665
CD86
CD86 molecule.
   
 
 0.662
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
   
 
 0.644
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
  
 0.617
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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