STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MBL2Mannose-binding protein C; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). (255 aa)    
Predicted Functional Partners:
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.995
LOC102132156
Uncharacterized protein.
   
 0.963
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 
 0.961
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
   
 0.958
ENSMFAP00000008465
C-type lectin domain-containing protein.
  
 
0.918
FCN3
Ficolin 3.
    
 0.893
C1S
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.815
CRP
Pentaxin.
   
 
 0.800
C1R
Complement C1r subcomponent heavy chain; C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system; Belongs to the peptidase S1 family.
   
 0.795
FCN1
Fibrinogen C-terminal domain-containing protein.
    
0.787
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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