STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP1BRas-related protein Rap-1b; GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family. (184 aa)    
Predicted Functional Partners:
RAPGEF4
Rap guanine nucleotide exchange factor 4.
    
 0.994
KRIT1
Uncharacterized protein.
    
 0.990
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
    
 0.982
RASGRP2
RAS guanyl releasing protein 2.
    
 0.981
RAPGEF2
Rap guanine nucleotide exchange factor 2.
   
 0.969
RAPGEF3
Rap guanine nucleotide exchange factor 3.
    
 0.969
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.969
RASGRP1
RAS guanyl releasing protein 1.
    
 0.966
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.966
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.965
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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