node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COPS2 | COPS3 | ENSMFAP00000033926 | ENSMFAP00000008660 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | 0.999 |
COPS2 | COPS4 | ENSMFAP00000033926 | ENSMFAP00000027787 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | 0.999 |
COPS2 | COPS5 | ENSMFAP00000033926 | ENSMFAP00000037074 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome subunit 5. | 0.986 |
COPS2 | COPS6 | ENSMFAP00000033926 | ENSMFAP00000029110 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | MPN domain-containing protein. | 0.982 |
COPS2 | COPS7A | ENSMFAP00000033926 | ENSMFAP00000038222 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome subunit 7A. | 0.985 |
COPS2 | COPS7B | ENSMFAP00000033926 | ENSMFAP00000042301 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome subunit 7B. | 0.986 |
COPS2 | COPS8 | ENSMFAP00000033926 | ENSMFAP00000024811 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | COP9 signalosome subunit 8. | 0.999 |
COPS2 | ENSMFAP00000006126 | ENSMFAP00000033926 | ENSMFAP00000006126 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | MPN domain-containing protein. | 0.973 |
COPS2 | ENSMFAP00000021271 | ENSMFAP00000033926 | ENSMFAP00000021271 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | Uncharacterized protein. | 0.979 |
COPS2 | GPS1 | ENSMFAP00000033926 | ENSMFAP00000022104 | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | PCI domain-containing protein. | 0.998 |
COPS3 | COPS2 | ENSMFAP00000008660 | ENSMFAP00000033926 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | Brain cDNA, clone: QnpA-16974, similar to human thyroid receptor interacting protein 15 (TRIP15). | 0.999 |
COPS3 | COPS4 | ENSMFAP00000008660 | ENSMFAP00000027787 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | COP9 signalosome complex subunit 4; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). Also involved in the deneddylation of non-cullin subunits such as STON2 (By similarity). The complex is also involved in phosphorylation of p53 [...] | 0.999 |
COPS3 | COPS5 | ENSMFAP00000008660 | ENSMFAP00000037074 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | COP9 signalosome subunit 5. | 0.988 |
COPS3 | COPS6 | ENSMFAP00000008660 | ENSMFAP00000029110 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | MPN domain-containing protein. | 0.982 |
COPS3 | COPS7A | ENSMFAP00000008660 | ENSMFAP00000038222 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | COP9 signalosome subunit 7A. | 0.992 |
COPS3 | COPS7B | ENSMFAP00000008660 | ENSMFAP00000042301 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | COP9 signalosome subunit 7B. | 0.986 |
COPS3 | COPS8 | ENSMFAP00000008660 | ENSMFAP00000024811 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | COP9 signalosome subunit 8. | 0.999 |
COPS3 | ENSMFAP00000006126 | ENSMFAP00000008660 | ENSMFAP00000006126 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | MPN domain-containing protein. | 0.974 |
COPS3 | ENSMFAP00000021271 | ENSMFAP00000008660 | ENSMFAP00000021271 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | Uncharacterized protein. | 0.975 |
COPS3 | GPS1 | ENSMFAP00000008660 | ENSMFAP00000022104 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2 (By similarity). The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association [...] | PCI domain-containing protein. | 0.999 |