STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)    
Predicted Functional Partners:
FOXO1
Forkhead box O1.
    
 0.978
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1.
    
 0.977
FOXO3
Forkhead box O3.
    
 0.976
TSC1
TSC complex subunit 1.
    
 0.976
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.976
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.974
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 0.974
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
0.974
TBC1D4
TBC1 domain family member 4.
    
 0.973
AKT1S1
AKT1 substrate 1.
   
 0.973
Your Current Organism:
Macaca fascicularis
NCBI taxonomy Id: 9541
Other names: M. fascicularis, Macaca cynomolgus, Macaca irus, crab eating macaque, crab-eating macaque, cynomolgus macaque, cynomolgus monkey, cynomolgus monkeys, long-tailed macaque
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.