node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CGA | FANCF | ENSMMUP00000072499 | ENSMMUP00000027400 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Fanconi anemia group F protein. | 0.816 |
CGA | FANCL | ENSMMUP00000072499 | ENSMMUP00000058806 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | FA complementation group L. | 0.810 |
CGA | FANCM | ENSMMUP00000072499 | ENSMMUP00000021700 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | FA complementation group M. | 0.985 |
CGA | FSHB | ENSMMUP00000072499 | ENSMMUP00000057162 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Follicle stimulating hormone subunit beta. | 0.998 |
CGA | FSHR | ENSMMUP00000072499 | ENSMMUP00000022620 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.994 |
CGA | LHB | ENSMMUP00000072499 | ENSMMUP00000005225 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Luteinizing hormone beta subunit. | 0.988 |
CGA | LHCGR | ENSMMUP00000072499 | ENSMMUP00000013586 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.972 |
CGA | SPP1 | ENSMMUP00000072499 | ENSMMUP00000011530 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Secreted phosphoprotein 1. | 0.901 |
CGA | TSHB | ENSMMUP00000072499 | ENSMMUP00000071277 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Thyroid stimulating hormone subunit beta. | 0.997 |
CGA | TSHR | ENSMMUP00000072499 | ENSMMUP00000025913 | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.989 |
FANCF | CGA | ENSMMUP00000027400 | ENSMMUP00000072499 | Fanconi anemia group F protein. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.816 |
FANCF | FANCL | ENSMMUP00000027400 | ENSMMUP00000058806 | Fanconi anemia group F protein. | FA complementation group L. | 0.999 |
FANCF | FANCM | ENSMMUP00000027400 | ENSMMUP00000021700 | Fanconi anemia group F protein. | FA complementation group M. | 0.999 |
FANCL | CGA | ENSMMUP00000058806 | ENSMMUP00000072499 | FA complementation group L. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.810 |
FANCL | FANCF | ENSMMUP00000058806 | ENSMMUP00000027400 | FA complementation group L. | Fanconi anemia group F protein. | 0.999 |
FANCL | FANCM | ENSMMUP00000058806 | ENSMMUP00000021700 | FA complementation group L. | FA complementation group M. | 0.999 |
FANCM | CGA | ENSMMUP00000021700 | ENSMMUP00000072499 | FA complementation group M. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.985 |
FANCM | FANCF | ENSMMUP00000021700 | ENSMMUP00000027400 | FA complementation group M. | Fanconi anemia group F protein. | 0.999 |
FANCM | FANCL | ENSMMUP00000021700 | ENSMMUP00000058806 | FA complementation group M. | FA complementation group L. | 0.999 |
FSHB | CGA | ENSMMUP00000057162 | ENSMMUP00000072499 | Follicle stimulating hormone subunit beta. | Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. | 0.998 |