STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MVB12BMultivesicular body subunit 12B. (380 aa)    
Predicted Functional Partners:
VPS37B
VPS37B subunit of ESCRT-I.
   
 0.994
VPS28
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.992
TSG101
ESCRT-I complex subunit TSG101.
    
 0.989
VPS37A
Vacuolar protein sorting-associated protein 37A isoform 1.
   
 0.979
VPS37C
VPS37C subunit of ESCRT-I.
   
 0.975
VPS37D
Vacuolar protein sorting-associated protein 37D.
   
 0.969
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.962
UEVLD
UEV and lactate/malate dehyrogenase domains.
    
 0.960
MVB12A
Multivesicular body subunit 12A.
    
0.950
VPS25
Vacuolar protein sorting 25 homolog.
    
 0.950
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.