STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM24Transcription intermediary factor 1-alpha isoform a. (1050 aa)    
Predicted Functional Partners:
TRIM28
Tripartite motif containing 28.
    
 
0.751
TRIM33
Tripartite motif containing 33.
   
 
0.723
ESR1
Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]
    
 0.708
SMAD4
Mothers against decapentaplegic homolog.
   
 0.660
TRIM8
Putative E3 ubiquitin-protein ligase TRIM8.
   
 
 0.643
SMARCAD1
annotation not available
   
 
 0.620
TRIM27
Zinc finger protein RFP.
    
 
 0.617
RARA
Retinoic acid receptor alpha isoform 1.
   
 0.613
LOC114669830
Histone H3; Belongs to the histone H3 family.
    
 0.601
TDRD9
Tudor domain containing 9.
    
 0.583
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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