STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAG6BCL2 associated athanogene 6. (1238 aa)    
Predicted Functional Partners:
GET4
Golgi to ER traffic protein 4.
    
 0.980
RNF126
Ring finger protein 126.
   
 
 0.935
UBXN1
UBX domain protein 1.
    
 
 0.927
FAF2
Fas associated factor family member 2.
   
 
 0.916
DESI1
PPPDE peptidase domain-containing protein 2.
    
   0.911
SGTA
Small glutamine rich tetratricopeptide repeat containing alpha.
   
 0.903
RNF115
E3 ubiquitin-protein ligase RNF115.
   
 
 0.782
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
    
 0.761
SGTB
Small glutamine rich tetratricopeptide repeat containing beta.
   
 0.712
HAVCR2
Hepatitis A virus cellular receptor 2.
    
 
 0.620
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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