node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PCDH9 | PPP1R10 | ENSMMUP00000007428 | ENSMMUP00000067273 | Protocadherin-9 isoform 1. | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | 0.782 |
PCDH9 | PPP1R11 | ENSMMUP00000007428 | ENSMMUP00000015892 | Protocadherin-9 isoform 1. | E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. | 0.589 |
PCDH9 | RUNX1 | ENSMMUP00000007428 | ENSMMUP00000075631 | Protocadherin-9 isoform 1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.569 |
PCDH9 | SETD4 | ENSMMUP00000007428 | ENSMMUP00000068305 | Protocadherin-9 isoform 1. | SET domain containing 4. | 0.803 |
PCDH9 | SLC37A3 | ENSMMUP00000007428 | ENSMMUP00000054345 | Protocadherin-9 isoform 1. | Sugar phosphate exchanger 3 isoform 1. | 0.791 |
PCDH9 | SLC5A7 | ENSMMUP00000007428 | ENSMMUP00000071109 | Protocadherin-9 isoform 1. | Solute carrier family 5 member 7; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.743 |
PCDH9 | ST6GAL2 | ENSMMUP00000007428 | ENSMMUP00000002397 | Protocadherin-9 isoform 1. | ST6 beta-galactoside alpha-2,6-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. | 0.784 |
PCDH9 | STX12 | ENSMMUP00000007428 | ENSMMUP00000009103 | Protocadherin-9 isoform 1. | FHA domain-containing protein. | 0.596 |
PPP1CA | PPP1CB | ENSMMUP00000022730 | ENSMMUP00000027076 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.980 |
PPP1CA | PPP1R10 | ENSMMUP00000022730 | ENSMMUP00000067273 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | 0.800 |
PPP1CA | PPP1R11 | ENSMMUP00000022730 | ENSMMUP00000015892 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. | 0.684 |
PPP1CA | STX12 | ENSMMUP00000022730 | ENSMMUP00000009103 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | FHA domain-containing protein. | 0.857 |
PPP1CB | PPP1CA | ENSMMUP00000027076 | ENSMMUP00000022730 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.980 |
PPP1CB | PPP1R10 | ENSMMUP00000027076 | ENSMMUP00000067273 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | 0.847 |
PPP1CB | PPP1R11 | ENSMMUP00000027076 | ENSMMUP00000015892 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. | 0.684 |
PPP1CB | STX12 | ENSMMUP00000027076 | ENSMMUP00000009103 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | FHA domain-containing protein. | 0.685 |
PPP1R10 | PCDH9 | ENSMMUP00000067273 | ENSMMUP00000007428 | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | Protocadherin-9 isoform 1. | 0.782 |
PPP1R10 | PPP1CA | ENSMMUP00000067273 | ENSMMUP00000022730 | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.800 |
PPP1R10 | PPP1CB | ENSMMUP00000067273 | ENSMMUP00000027076 | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.847 |
PPP1R10 | PPP1R11 | ENSMMUP00000067273 | ENSMMUP00000015892 | Serine/threonine-protein phosphatase 1 regulatory subunit 10; Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) [...] | E3 ubiquitin-protein ligase PPP1R11; Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. | 0.751 |