node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSM1 | NR0B1 | ENSMMUP00000017990 | ENSMMUP00000016782 | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | 0.660 |
LSM1 | NR5A1 | ENSMMUP00000017990 | ENSMMUP00000018545 | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | Nuclear receptor subfamily 5 group A member 1. | 0.785 |
LSM1 | PRKACA | ENSMMUP00000017990 | ENSMMUP00000054168 | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.552 |
LSM1 | PRKACB | ENSMMUP00000017990 | ENSMMUP00000059748 | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. | 0.632 |
LSM1 | PRKACG | ENSMMUP00000017990 | ENSMMUP00000026815 | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. | 0.552 |
NCOA2 | NR0B1 | ENSMMUP00000021016 | ENSMMUP00000016782 | Nuclear receptor coactivator. | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | 0.429 |
NCOA2 | NR5A1 | ENSMMUP00000021016 | ENSMMUP00000018545 | Nuclear receptor coactivator. | Nuclear receptor subfamily 5 group A member 1. | 0.845 |
NR0B1 | LSM1 | ENSMMUP00000016782 | ENSMMUP00000017990 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | 0.660 |
NR0B1 | NCOA2 | ENSMMUP00000016782 | ENSMMUP00000021016 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | Nuclear receptor coactivator. | 0.429 |
NR0B1 | NR5A1 | ENSMMUP00000016782 | ENSMMUP00000018545 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | Nuclear receptor subfamily 5 group A member 1. | 0.993 |
NR0B1 | SOX9 | ENSMMUP00000016782 | ENSMMUP00000073101 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. | 0.594 |
NR0B1 | WT1 | ENSMMUP00000016782 | ENSMMUP00000012938 | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | WT1 transcription factor. | 0.720 |
NR0B2 | NR5A1 | ENSMMUP00000013473 | ENSMMUP00000018545 | Nuclear receptor subfamily 0 group B member 2. | Nuclear receptor subfamily 5 group A member 1. | 0.858 |
NR0B2 | PPARGC1A | ENSMMUP00000013473 | ENSMMUP00000060440 | Nuclear receptor subfamily 0 group B member 2. | PPARG coactivator 1 alpha. | 0.434 |
NR5A1 | LSM1 | ENSMMUP00000018545 | ENSMMUP00000017990 | Nuclear receptor subfamily 5 group A member 1. | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. | 0.785 |
NR5A1 | NCOA2 | ENSMMUP00000018545 | ENSMMUP00000021016 | Nuclear receptor subfamily 5 group A member 1. | Nuclear receptor coactivator. | 0.845 |
NR5A1 | NR0B1 | ENSMMUP00000018545 | ENSMMUP00000016782 | Nuclear receptor subfamily 5 group A member 1. | Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. | 0.993 |
NR5A1 | NR0B2 | ENSMMUP00000018545 | ENSMMUP00000013473 | Nuclear receptor subfamily 5 group A member 1. | Nuclear receptor subfamily 0 group B member 2. | 0.858 |
NR5A1 | PPARGC1A | ENSMMUP00000018545 | ENSMMUP00000060440 | Nuclear receptor subfamily 5 group A member 1. | PPARG coactivator 1 alpha. | 0.822 |
NR5A1 | PRKACA | ENSMMUP00000018545 | ENSMMUP00000054168 | Nuclear receptor subfamily 5 group A member 1. | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.921 |