STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POU1F1Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'; Belongs to the POU transcription factor family. Class- 1 subfamily (317 aa)    
Predicted Functional Partners:
LHX4
Uncharacterized protein; LIM homeobox 4
   
 
 0.885
LHX3
LIM homeobox 3
   
 
 0.848
GHRHR
Growth hormone releasing hormone receptor
   
  
 0.826
TSHB
Thyroid stimulating hormone beta subunit
   
  
 0.822
TBX19
Uncharacterized protein
   
  
 0.816
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation
   
  
 0.810
CGA
Glycoprotein hormones alpha chain ; Belongs to the glycoprotein hormones subunit alpha family
   
  
 0.802
HESX1
HESX homeobox 1
   
 
 0.772
IL17RD
Interleukin 17 receptor D
      
 0.768
ARL11
ADP-ribosylation factor-like 11; Belongs to the small GTPase superfamily. Arf family
    
 
 0.767
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Macaca mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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