STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POU1F1Pituitary-specific positive transcription factor 1; Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'. (317 aa)    
Predicted Functional Partners:
PROP1
PROP paired-like homeobox 1.
    
 
 0.892
PRL
Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation.
   
  
 0.774
TBX19
T-box transcription factor 19.
   
 0.747
GHRHR
Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.743
HESX1
HESX homeobox 1.
    
 
 0.732
CRX
Cone-rod homeobox.
   
 
 0.724
IL17RD
Interleukin 17 receptor D.
   
  
 0.715
TENM2
Teneurin transmembrane protein 2.
      
 0.690
LHX3
LIM homeobox 3.
   
 
 0.668
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
      
 0.651
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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