STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK1Tyrosine-protein kinase. (1154 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.999
STAT3
Signal transducer and activator of transcription.
   
 0.998
STAT1
Signal transducer and activator of transcription.
   
 0.998
IL10RA
Interleukin 10 receptor subunit alpha.
   
 0.998
TYK2
Tyrosine-protein kinase.
  
 
0.997
STAT2
Signal transducer and activator of transcription.
   
 0.996
SOCS1
Suppressor of cytokine signaling 1.
   
 0.995
STAT5A
Signal transducer and activator of transcription.
   
 0.995
SOCS3
Suppressor of cytokine signaling 3.
   
 0.995
STAT5B
Signal transducer and activator of transcription.
   
 0.994
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.