STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPOPSpeckle type BTB/POZ protein. (413 aa)    
Predicted Functional Partners:
CUL3
Cullin-3; Belongs to the cullin family.
   
 0.989
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.907
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.896
PTEN
Uncharacterized protein.
   
 
 0.872
GLI3
GLI family zinc finger 3.
   
 0.860
GLI2
GLI family zinc finger 2.
   
 0.854
GLI1
Zinc finger protein GLI1 isoform 1.
   
 0.836
UBE2I
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.817
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
   
 0.812
TP53BP1
Tumor protein p53 binding protein 1.
   
 
 0.806
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.