STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E2F4Transcription factor E2F4. (416 aa)    
Predicted Functional Partners:
RBL2
RB transcriptional corepressor like 2.
   
 0.997
TFDP1
Transcription factor.
   
 0.992
RBL1
RB transcriptional corepressor like 1.
   
 0.992
TFDP2
Uncharacterized protein.
   
 0.986
RB1
Retinoblastoma-associated protein.
   
 0.986
SMAD4
Mothers against decapentaplegic homolog.
    
 0.980
SMAD3
Mothers against decapentaplegic homolog.
    
 0.975
E2F5
E2F transcription factor 5.
  
 
0.966
SMAD2
Mothers against decapentaplegic homolog.
    
 0.957
ENSMMUP00000061681
Transcription factor.
   
 0.934
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.