| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM40_124 | DM40_1277 | DM40_124 | DM40_1277 | NAD dependent epimerase/dehydratase family protein. | ATPase associated with various cellular activities family protein. | 0.420 |
| DM40_1277 | DM40_124 | DM40_1277 | DM40_124 | ATPase associated with various cellular activities family protein. | NAD dependent epimerase/dehydratase family protein. | 0.420 |
| DM40_1277 | DM40_1278 | DM40_1277 | DM40_1278 | ATPase associated with various cellular activities family protein. | NUDIX domain protein; Belongs to the Nudix hydrolase family. | 0.803 |
| DM40_1277 | DM40_1705 | DM40_1277 | DM40_1705 | ATPase associated with various cellular activities family protein. | Prephenate dehydrogenase family protein. | 0.545 |
| DM40_1277 | argJ | DM40_1277 | DM40_1276 | ATPase associated with various cellular activities family protein. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.784 |
| DM40_1277 | hisE | DM40_1277 | DM40_1150 | ATPase associated with various cellular activities family protein. | histidine_hisI: phosphoribosyl-ATP diphosphatase. | 0.416 |
| DM40_1277 | hisZ | DM40_1277 | DM40_2400 | ATPase associated with various cellular activities family protein. | ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.518 |
| DM40_1277 | ilvC | DM40_1277 | DM40_2913 | ATPase associated with various cellular activities family protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.514 |
| DM40_1277 | secA | DM40_1277 | DM40_1275 | ATPase associated with various cellular activities family protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.511 |
| DM40_1278 | DM40_1277 | DM40_1278 | DM40_1277 | NUDIX domain protein; Belongs to the Nudix hydrolase family. | ATPase associated with various cellular activities family protein. | 0.803 |
| DM40_1278 | argJ | DM40_1278 | DM40_1276 | NUDIX domain protein; Belongs to the Nudix hydrolase family. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.786 |
| DM40_1278 | secA | DM40_1278 | DM40_1275 | NUDIX domain protein; Belongs to the Nudix hydrolase family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.511 |
| DM40_1705 | DM40_1277 | DM40_1705 | DM40_1277 | Prephenate dehydrogenase family protein. | ATPase associated with various cellular activities family protein. | 0.545 |
| DM40_1705 | argJ | DM40_1705 | DM40_1276 | Prephenate dehydrogenase family protein. | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.405 |
| DM40_1705 | hisE | DM40_1705 | DM40_1150 | Prephenate dehydrogenase family protein. | histidine_hisI: phosphoribosyl-ATP diphosphatase. | 0.556 |
| DM40_1705 | hisZ | DM40_1705 | DM40_2400 | Prephenate dehydrogenase family protein. | ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.629 |
| DM40_1705 | ilvC | DM40_1705 | DM40_2913 | Prephenate dehydrogenase family protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.414 |
| argJ | DM40_1277 | DM40_1276 | DM40_1277 | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | ATPase associated with various cellular activities family protein. | 0.784 |
| argJ | DM40_1278 | DM40_1276 | DM40_1278 | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | NUDIX domain protein; Belongs to the Nudix hydrolase family. | 0.786 |
| argJ | DM40_1705 | DM40_1276 | DM40_1705 | Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | Prephenate dehydrogenase family protein. | 0.405 |