node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CMPK1 | CMPK2 | ENSPANP00000006710 | ENSPANP00000012839 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Cytidine/uridine monophosphate kinase 2. | 0.947 |
CMPK1 | PNP | ENSPANP00000006710 | ENSPANP00000014578 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.471 |
CMPK1 | UCK1 | ENSPANP00000006710 | ENSPANP00000018823 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase 1. | 0.915 |
CMPK1 | UCK2 | ENSPANP00000006710 | ENSPANP00000005864 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.931 |
CMPK1 | UCKL1 | ENSPANP00000006710 | ENSPANP00000014401 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.921 |
CMPK1 | UMPS | ENSPANP00000006710 | ENSPANP00000009016 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uridine monophosphate synthetase. | 0.929 |
CMPK1 | UPRT | ENSPANP00000006710 | ENSPANP00000002680 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Uracil phosphoribosyltransferase homolog. | 0.940 |
CMPK2 | CMPK1 | ENSPANP00000012839 | ENSPANP00000006710 | Cytidine/uridine monophosphate kinase 2. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.947 |
CMPK2 | TYMP | ENSPANP00000012839 | ENSPANP00000013709 | Cytidine/uridine monophosphate kinase 2. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.433 |
CMPK2 | UCK1 | ENSPANP00000012839 | ENSPANP00000018823 | Cytidine/uridine monophosphate kinase 2. | Uridine-cytidine kinase 1. | 0.916 |
CMPK2 | UCK2 | ENSPANP00000012839 | ENSPANP00000005864 | Cytidine/uridine monophosphate kinase 2. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.916 |
CMPK2 | UCKL1 | ENSPANP00000012839 | ENSPANP00000014401 | Cytidine/uridine monophosphate kinase 2. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.905 |
CMPK2 | UMPS | ENSPANP00000012839 | ENSPANP00000009016 | Cytidine/uridine monophosphate kinase 2. | Uridine monophosphate synthetase. | 0.948 |
CMPK2 | UPRT | ENSPANP00000012839 | ENSPANP00000002680 | Cytidine/uridine monophosphate kinase 2. | Uracil phosphoribosyltransferase homolog. | 0.949 |
DPYD | PNP | ENSPANP00000006094 | ENSPANP00000014578 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.930 |
DPYD | TYMP | ENSPANP00000006094 | ENSPANP00000013709 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.998 |
DPYD | UCK1 | ENSPANP00000006094 | ENSPANP00000018823 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine-cytidine kinase 1. | 0.546 |
DPYD | UCK2 | ENSPANP00000006094 | ENSPANP00000005864 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.514 |
DPYD | UCKL1 | ENSPANP00000006094 | ENSPANP00000014401 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine-cytidine kinase; Belongs to the uridine kinase family. | 0.739 |
DPYD | UMPS | ENSPANP00000006094 | ENSPANP00000009016 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. | Uridine monophosphate synthetase. | 0.993 |