STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC; Belongs to the type I cytokine receptor family. Type 3 subfamily (330 aa)    
Predicted Functional Partners:
IL12A
Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC
    
 0.994
IL12RB2
Interleukin 12 receptor, beta 2
    
 0.974
IL23R
Interleukin 23 receptor
    
 0.972
IL23A
Interleukin 23, alpha subunit p19
    
 0.955
IFNGR2
Papio anubis interferon gamma receptor 2 (interferon gamma transducer 1) (IFNGR2), mRNA
     
 0.889
IFNGR1
Interferon gamma receptor 1
     
 0.869
IL2RG
Interleukin 2 receptor, gamma
   
 
 0.856
CSF3R
Colony stimulating factor 3 receptor (granulocyte)
     
 0.853
GHR
Growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity)
     
 0.850
CNTFR
Ciliary neurotrophic factor receptor
     
0.848
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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