STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGTAngiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. (485 aa)    
Predicted Functional Partners:
AGTR1
Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
AGTR2
Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
REN
Renin; Belongs to the peptidase A1 family.
   
 0.997
ACE2
Angiotensin-converting enzyme.
    
 0.988
EDNRA
Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.
    
 0.982
ACE
Angiotensin-converting enzyme.
    
 0.981
BDKRB2
Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family.
    
 0.978
EDNRB
Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.
    
 0.970
MAS1
MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.964
F2RL3
F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
  0.949
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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