STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINA3Serpin family A member 3; Belongs to the serpin family. (448 aa)    
Predicted Functional Partners:
KLK3
Kallikrein related peptidase 3; Belongs to the peptidase S1 family.
    
 0.855
G3RD46_GORGO
Cathepsin G; Belongs to the peptidase S1 family.
    
 0.826
G3R512_GORGO
Chymotrypsinogen B2; Belongs to the peptidase S1 family.
    
 0.802
G3RYX4_GORGO
Chymotrypsinogen B1; Belongs to the peptidase S1 family.
    
 0.801
ENSGGOP00000029832
Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.772
BPIFA1
BPI fold containing family A member 1.
     
 0.768
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.725
G3RGJ6_GORGO
Alpha-1-acid glycoprotein; Functions as transport protein in the blood stream. Belongs to the calycin superfamily. Lipocalin family.
   
 0.720
A2M
Alpha-2-macroglobulin.
   
 0.707
ALB
Albumin.
   
 0.706
Your Current Organism:
Gorilla gorilla
NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.